Predictive Value of Novel Inflammation-Based Biomarkers for Pulmonary Hypertension in the Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Table 4

Relationship between the statistically different indicators and NT-proBNP (or PASP).

Parameters	NT-proBNP		PASP
	value	value	value	value
Lymphocyte (10^9/l)	-0.386	<0.001	-0.265	0.007
NLR	0.340	<0.001	0.087	0.389
PLR	0.355	<0.001	0.235	0.018
SII	0.288	<0.001	0.069	0.494
NT-proBNP (pg/ml)	1	—	0.500	<0.001
PaCO2 (mmHg)	0.268	<0.001	0.403	<0.001
HCO3^- (mmol/l)	0.280	<0.001	0.427	<0.001
Lac (mmol/l)	0.122	0.100	0.013	0.894
D-Dimer (μg/ml)	0.318	<0.001	0.220	0.027

Abbreviations: PASP—pulmonary arterial systolic pressure; PaCO₂—partial pressure of carbon dioxide; HCO₃^-—bicarbonate ion; NLR—neutrophil-to-lymphocyte ratio; PLR—platelet-to-lymphocyte ratio; SII—systemic-immune-inflammation index; PaCO₂—partial pressure of carbon dioxide; HCO₃^-—bicarbonate ion; Lac—lactic acid.