Localized Amyloidosis of the Upper Aerodigestive Tract: Complex Analysis of the Cellular Infiltrate and the Amyloid Mass

Figure 2

List and relative distribution of the top 21 and 2 low abundance proteins observed by nano-HPLC-MS(MS) and given in percent in the five cases; normalized to the top 21 proteins. Known amyloidogenic proteins, like ApoAIV (5), LC κ and λ (14 and 15), ApoAI (21), PA (102), and AA (194) partly examined by immunohistochemistry, were also present in the amyloid material in different concentrations. Note that not just LCs but also ApoAIV and ApoAI with higher intensity and PA and AA with much less intensity also participated in the formation of the lesion. The numbers at the bottom of the columns indicate the mean frequency of the particular protein.