PKM2 Promotes Breast Cancer Progression by Regulating Epithelial Mesenchymal Transition

<div>PKM2 is required for breast cancer cell migration and invasion. Cell migration (a) and invasion (b) of MDA-MB-231 cells after PKM2 knockdown was determined by transwell assay. Cell migration (c) and invasion (d) of MCF-7 cells after PKM2 knockdown was determined by transwell assay. Representative images from the migration and invasion of control and PKM2-KD cells of MDA-MB-231 and MCF-7 cells (top panel). Cell migration and invasion are expressed as a percentage of control (bottom panel). Cells were counted for at least five random microscope fields. 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Analytical Cellular Pathology

fig4

Figure 4

Figure 4: PKM2 Promotes Breast Cancer Progression by Regulating Epithelial Mesenchymal Transition 