Research Article

Altered Expression of Three EGFR Posttranslational Regulators MDGI, MIG6, and EIG121 in Invasive Breast Carcinomas

Figure 1

Results obtained by RT-PCR showed that MIG6 is mainly underexpressed in invasive breast carcinomas and more particularly in the HR+/HER2- subtype. Both overexpression and underexpression were observed for the two other genes: MDGI and EIG121 are mainly overexpressed in the two HR+ subtypes. TNCs showed high frequency of EIG121 underexpression.