N-trans-Feruloyloctopamine Wakes Up BBC3, DDIT3, CDKN1A, and NOXA Signals to Accelerate HCC Cell Apoptosis

Figure 2

FO can inhibit cell proliferation and stimulate apoptosis in Huh7 cells. (a, b) Cell index values of Huh7 and Hep3B cells cultivated for 90 h. Electrical impedance was measured throughout the cultivation period at a 15 min frequency. Green and blue curves represent the proliferation of Huh7 and Hep3B cells treated with DMSO and FO, respectively. The mean cell index values with SE for the three repetitions in each group. (c, d) Hep3B and Huh7 cells were treated with DMSO for 24 hours, FO for 24 hours and 48 hours, and then stained with Annexin V and PI.

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