Establishment and Mechanism Study of a Primary Ovarian Insufficiency Mouse Model Using Lipopolysaccharide

<div>LPS stimulation induced granulosa cell apoptosis in mouse ovaries. (a) TUNEL assay was performed to examine granulosa cell apoptosis in the mouse ovaries. Representative images are shown, blue represents nuclear, and green represents apoptosis granule. Magnification 100x. (b) qRT-PCR and (c) Western blotting were performed to determine mRNA and protein expression of Bax and Bcl-2 in mouse ovaries. 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Analytical Cellular Pathology

fig4

Figure 4

Figure 4: Establishment and Mechanism Study of a Primary Ovarian Insufficiency Mouse Model Using Lipopolysaccharide 