Nuclear Morphological Characteristics in Breast Cancer: Correlation with Hormone Receptor and Human Epidermal Growth Factor Receptor 2

Table 1

Patient characteristics.

Characteristics	HR+/HER2-	HR-/HER2+	All ()	value
Age, median (range), years			50.9 (26-83)	0.193
≤50	48	25	73
>50	38	31	69
Sex
Female			142
Clinical stage				0.130
I	5	0	5
II	36	22	58
III	31	28	59
IV	14	6	20
Histological type
Invasive carcinoma of no specific type			142
Tumor size, cm				0.222
≤2	27	16	43
	57	35	92
> 5	2	5	7
Number of metastic lymph nodes				0.637
< 5	68	43	111
	15	9	24
≥ 10	3	4	7
Distant metastases
Yes	8	2	10	0.316
None	78	54	132

HR+/HER2-: hormone receptors-positive and human epidermal growth factor receptor 2-negative; HR-/HER2+: hormone receptors-negative and human epidermal growth factor receptor 2-positive. By Chi-square test, others by Fisher exact test.