Research Article
Evaluation of the Prognostic Value of Solute Carrier Family 34 Member 2 “SLC34A2” in Papillary Thyroid Carcinoma: An Immunohistochemical Study
Table 2
Relationship between SLC34A2 IHC expression and clinicopathological characteristics.
| | SLC34A2 | value | Significance | Low | High |
| Age group | <55 | 56 | 45.9% | 66 | 54.1% | ≤0.001 | HS | ≥55 | 19 | 16.4% | 97 | 83.6% |
| Gender | Male | 8 | 16.7% | 40 | 83.3% | 0.013 | S | Female | 67 | 35.3% | 123 | 64.7% |
| Lymph node at presentation | N0 | 54 | 32.9% | 110 | 67.1% | 0.484‡ | NS | N1 | 21 | 28.4% | 53 | 71.6% |
| Lymphovascular invasion | Negative | 59 | 30.7% | 133 | 69.3% | 0.595‡ | NS | Positive | 16 | 34.8% | 30 | 65.2% |
| Capsular invasion | Negative | 69 | 54.3% | 58 | 45.7% | ≤0.001 | HS | Positive | 6 | 5.4% | 105 | 94.6% |
| PTC variants | Classic | 54 | 31.4% | 118 | 68.6% | 0.988 | NS | Follicular | 16 | 31.4% | 35 | 68.6% | Other | 5 | 33.3% | 10 | 66.7% |
| Extrathyroid extension | Negative | 74 | 35.7% | 133 | 64.3% | ≤0.001 | HS | Positive | 1 | 3.2% | 30 | 96.8% |
| Stage | I | 72 | 38.1% | 117 | 61.9% | ≤0.001 | HS | II | 3 | 7.9% | 35 | 92.1% | III | 0 | 0.0% | 11 | 100.0% |
| Tumor size (cm) | ≤4 | 62 | 54.4% | 52 | 45.6% | ≤0.001 | HS | >4 | 13 | 10.5% | 111 | 89.5% |
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‡Student’s -test. Chi-square test. Solute carrier family 34 member A2 (SLC34A2); immunohistochemical (IHC); papillary thyroid carcinoma (PTC); highly significant (HS); significant (S); not significant (NS). |