Exploration of the Immune-Related Signatures and Immune Infiltration Analysis in Melanoma

Table 2

Identification of 12 hub prognostic immune signatures based on a multivariate regression method.

Gene symbol	Description	coef	HR	HR.95L	HR.95H
HLA-DPB1	HLA class II histocompatibility antigen, DP beta 1 chain	-0.219	0.803	0.693	0.930	0.003
IGHV3-21	Immunoglobulin heavy variable 3-21	-0.087	0.917	0.819	1.026	0.131
IGKV4-1	Immunoglobulin kappa variable 4-1	0.080	1.084	0.977	1.202	0.129
IGLC2	Immunoglobulin lambda constant 2	-0.120	0.887	0.795	0.990	0.033
IGLV2-11	Immunoglobulin lambda variable 2-11	0.120	1.128	1.009	1.260	0.034
IL27RA	Interleukin-27 receptor subunit alpha	-0.182	0.833	0.739	0.940	0.003
NFATC4	Nuclear factor of activated T cells, cytoplasmic 4	0.180	1.198	1.036	1.384	0.015
NTF4	Neurotrophin-4	-0.932	0.394	0.118	1.309	0.128
PGLYRP4	Peptidoglycan recognition protein 4	0.326	1.385	0.996	1.925	0.053
RAC2	Ras-related protein Rac2	0.131	1.140	0.998	1.301	0.053
SLPI	Antileukoproteinase	0.102	1.107	1.007	1.217	0.035
STAT1	Signal transducer and activator of transcription 1-alpha/beta	-0.103	0.902	0.787	1.033	0.135