Anlotinib Suppresses Oral Squamous Cell Carcinoma Growth and Metastasis by Targeting the RAS Protein to Inhibit the PI3K/Akt Signalling Pathway

<div>Anlotinib induced apoptosis in HSC-3 cells. After HSC-3 cells were treated with different concentrations (0, 1, 2, and 4 <i>μ</i>M/L) of anlotinib for 72 h, apoptosis was detected by Hoechst 33258 staining, which showed that apoptotic cells gradually increased from low to high drug concentrations.</div>

Analytical Cellular Pathology

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Figure 5

Figure 5: Anlotinib Suppresses Oral Squamous Cell Carcinoma Growth and Metastasis by Targeting the RAS Protein to Inhibit the PI3K/Akt Signalling Pathway 

Figure 5 | Anlotinib Suppresses Oral Squamous Cell Carcinoma Growth and Metastasis by Targeting the RAS Protein to Inhibit the PI3K/Akt Signalling Pathway 