Research Article

IMP3 Immunohistochemical Expression in Inverted Papilloma and Inverted Papilloma-Associated Sinonasal Squamous Cell Carcinoma

Table 3

ROC curve using IMP3 and Ki-67 to differentiate SCC cases from noncancerous cases.

IHC markerAUC (CI)SensitivitySpecificity+PV-PV value (sig)

0.971 (0.918 to 0.994)100.0081.5246.9100.0<0.0001 (HS)
0.828 (0.743 to 0.894)100.0065.2231.9100.0<0.0001 (HS)

AUC: area under the curve; CI: confidence interval; +PV: positive predictive value; -PV: negative predictive value; sig: significance; HS: highly significant.