Identification of a Seven-lncRNA-mRNA Signature for Recurrence and Prognostic Prediction in Relapsed Acute Lymphoblastic Leukemia Based on WGCNA and LASSO Analyses

Table 2

The optimal prognostic signature.

Symbol	Module	Expression	Type	Multivariate Cox regression analysis			LASSO coefficient
				HR	95% CI	value
LINC00652	Turquoise	Downregulated	lncRNA	0.980	0.949-0.993		-0.00432
INSL3	Green	Downregulated	mRNA	1.008	1.004-1.012		0.00739
NIPAL2	Yellow	Upregulated	mRNA	1.004	1.001-1.007		0.00362
REN	Turquoise	Downregulated	mRNA	1.024	1.004-1.045		0.02222
RIMS2	Turquoise	Upregulated	mRNA	1.011	1.005-1.033		0.00769
RPRM	Turquoise	Upregulated	mRNA	1.020	1.006-1.035		0.01680
SNAP91	Turquoise	Downregulated	mRNA	1.050	1.001-1.101		0.02990

HR: hazard ratio; CI: confidence interval; LASSO: least absolute shrinkage and selection operator.