Actin-Binding Proteins as Potential Biomarkers for Chronic Inflammation-Induced Cancer Diagnosis and Therapy

Table 3

ABPs involved in different cancer diseases and their expression.

Cancer	ABPs	Correlation	Ref.
Breast cancer	ACTN4, AFAP-110, CORO1C, girdin, transgelin, ANLN, ARP2	Positive correlations	[85, 87–89, 92, 165, 166]
Gastric cancer	Fascin, fascin-1, ANLN, CAPZA1, CORO1C, YAP, ARP3	Positive correlations	[31, 94, 96–99]
Lung cancer	VASP, profilin-1, cofilin-1, profilin, fascin, ezrin, TWF1, fascin-1, ARP2	TWF1 and cofilin-1: negative correlation; VASP, profilin-1, profilin, fascin, ezrin, and fascin-1: positive correlations	[100, 102, 103, 105–107, 166]
Prostate cancer	SWAP70, PDLIM4, CORO1C, transgelin	PDLIM4: negative correlation; SWAP70, CORO1C, and transgelin: positive correlations	[111–113, 165]
Liver cancer	ANLN, 50 kDa protein	Positive correlations	[116, 117]
Pancreatic cancer	Destrin, cortactin, fascin-1	Positive correlations	[121, 122]
Esophageal cancer	Paxillin, tensin, villin-1, talin, profilin-1, profilin-2, fascin, girdin	Positive correlations	[124–128]
Melanoma	Espin, cortactin, filamin	Positive correlations	[132–135]
Colorectal cancer	Transgelin, ARP2/3, fascin	Positive correlations	[137, 140, 166]
Basal cell carcinoma, trichoblastoma, and trichoepithelioma	Drebrin	Positive correlations	[138]