Review Article

Long Noncoding RNAs Regulate the Radioresistance of Breast Cancer

Figure 2

lncRNAs downregulate or upregulate BRCA radioresistance via different roles. Major mechanisms regulating the tumor radioresistance of lncRNAs: (1) DNA double-strand repair, (2) IR-induced apoptosis, (3) IR-induced autophagy, (4) cell cycle, and (5) others: glycolysis, the Wnt/β-catenin pathway, SRSP.