miR-142-3p Modulates Cell Invasion and Migration via PKM2-Mediated Aerobic Glycolysis in Colorectal Cancer

Figure 3

PKM2 modulates colorectal cancer cell invasion and migration via aerobic glycolysis pathway. (a) PKM2 expression in human colorectal cancer tissues and normal adjacent tissues was determined by immunohistochemistry. (b) PKM2 expressions were measured in HCT116 and T84 cells stably overexpressing PKM2. Data were presented as . and . (c) Glucose uptake in HCT116 and T84 cells stably overexpressing PKM2 was measured by ELISA. Data were presented as . and . (d) Lactate production in HCT116 and T84 cells stably overexpressing PKM2 was measured by ELISA. Data were presented as . and . (e) Transwell assays were performed to determined invasion and migration of HCT116 and T84 cells stably overexpressing PKM2. , , and .

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