Research Article

miR-142-3p Modulates Cell Invasion and Migration via PKM2-Mediated Aerobic Glycolysis in Colorectal Cancer

Figure 4

miR-142-3p regulates colorectal cancer cell progression via PKM2-mediated glycolysis. (a) PKM2 expression was measured in HCT116 and T84 cell stably overexpression miR-142-3p or/and PKM2. Data were presented as . , , , and . (b) Transwell assays were performed to determined invasion and migration in HCT116 and T84 cell stably overexpression miR-142-3p or/and PKM2. (c) Glucose uptake in HCT116 and T84 cell stably overexpression miR-142-3p or/and PKM2 was measured by ELISA. Data were presented as . , , , and . (d) Lactate production in HCT116 and T84 cell stably overexpression miR-142-3p or/and PKM2 was measured by ELISA. Data were presented as . , , , and . , , and .
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