Metformin Protects against Spinal Cord Injury and Cell Pyroptosis via AMPK/NLRP3 Inflammasome Pathway

Figure 2

Metformin activates the AMPK/NLRP3 signaling pathway in spinal cord neurons. (a–c) Representative Western blots and quantification data of the levels of p-AMPK and p-ACC in the spinal cord neurons from each group. All data represented the , , . (d–h) Representative Western blots and quantification data of the expression of NLRP3, ASC, Caspase 1, and IL-1β in the spinal cord neurons from each group. All data represent the , , . (i, j) Immunofluorescence examination was utilized to recognize the staining power of antibodies focusing on NeuN and p-AMPK. Scale bars represent 40 μm. , .

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