Research Article
“Derived Multiple Allogeneic Protein Paracrine Signaling (d-MAPPS)” Enhances T Cell-Driven Immune Response to Murine Mammary Carcinoma
Figure 3
d-MAPPS did not significantly alter phenotype and function of tumor-infiltrated NK cells and macrophages. Flow cytometry analysis and intracellular staining of (a) tumor-infiltrated CD178+, (b) granzyme B+, (c) IFN-γ+, IL-17+ NK1.1+NK cells and (e) IL-12+, (f) TNF-α+, (g) IL-10+, (h) CD80+, (i) CD86+, and (j) I-A+ F4/80+ macrophages in the tumors of 4T1+saline-treated (black bars) and 4T1+d-MAPPS-treated mice (white bars). Data are presented as ( mice/group).
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