Chemoprevention of 4NQO-Induced Mouse Tongue Carcinogenesis by AKT Inhibitor through the MMP-9/RhoC Signaling Pathway and Autophagy

<div>MK2206 2HCl suppressed the OSCC cell invasion ability. (a) MK2206 2HCl inhibited CAL27 cell invasive ability by Transwell invasion assay. (b) MK2206 2HCl inhibited SCC25 cell invasive ability by Transwell invasion assay. 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Magnification ×400.</div>

Analytical Cellular Pathology

fig10

Figure 10

Figure 10: Chemoprevention of 4NQO-Induced Mouse Tongue Carcinogenesis by AKT Inhibitor through the MMP-9/RhoC Signaling Pathway and Autophagy 