Research Article

Diagnostic and Prognostic Impact of Progesterone Receptor Immunohistochemistry: A Study Evaluating More Than 16,000 Tumors

Table 2

Ranking of PR immunostaining in tumors (only tumor entities with 3 evaluable tumors were included in the ranking. Mammary tumors are italicized. Gynecological tumors are in bold).

Ranking PR≥ weak (%)≥ mod (%)Strong (%)

Tubular carcinoma of the breast82.673.965.2
Granulosa cell tumor of the ovary81.151.421.6
Mucinous carcinoma of the breast76.568.660.8
Phyllodes tumor of the breast73.073.054.1
Sertoli Leydig cell tumor of the ovary66.70.00.0
Endometrioid endometrial carcinoma66.544.731.0
Endometrioid carcinoma of the ovary62.043.529.3
Invasive breast carcinoma of no special type57.146.535.8
Lobular carcinoma of the breast57.047.037.4
Pancreas, neuroendocrine tumor (NET)54.337.227.7
Leydig cell tumor of the ovary50.00.00.0
Leydig cell tumor of the testis36.73.30.0
Pancreas, neuroendocrine carcinoma (NEC)35.728.614.3
Carcinosarcoma of the ovary34.111.44.5
Serous carcinoma of the ovary32.110.05.8
Endometrial serous carcinoma20.65.92.9
Medullary thyroid carcinoma20.43.71.9
Endometrial carcinoma, high grade, G316.78.38.3
Small cell neuroendocrine carcinoma of the prostate16.70.00.0
Small cell carcinoma of the lung12.56.30.0
Angiomyolipoma12.53.43.4
Carcinosarcoma of the uterus12.27.37.3
Medullary carcinoma of the breast12.19.16.1
Adrenal cortical carcinoma11.50.00.0
Follicular thyroid carcinoma11.36.02.6
Clear cell carcinoma of the ovary11.14.42.2
Leiomyosarcoma10.88.18.1
Papillary thyroid carcinoma10.61.60.5
Adenocarcinoma of the cervix9.54.80.0
Adenoma of the thyroid gland7.12.70.0
Oncocytoma6.90.40.0
Myoepithelial carcinoma of the salivary gland5.95.90.0
Appendix, neuroendocrine tumor (NET)5.95.90.0
Mucinous carcinoma of the ovary5.25.25.2
Brenner tumor5.05.05.0
Teratoma4.94.94.9
Neurofibroma4.80.00.0
Chromophobe renal cell carcinoma4.61.31.3
Adrenal cortical adenoma4.52.32.3
Small cell neuroendocrine carcinoma of the bladder4.30.00.0
Clear cell (tubulo) papillary renal cell carcinoma4.24.20.0
Adenocarcinoma NOS of the salivary gland2.52.51.2
Anaplastic thyroid carcinoma2.30.00.0
Ductal adenocarcinoma of the pancreas2.21.20.6
Urothelial carcinoma of the kidney pelvis1.60.00.0
Sarcoma, not otherwise specified (NOS)1.41.41.4
Squamous cell carcinoma of the cervix0.80.00.0
Adenocarcinoma of the prostate (recurrence)0.40.00.0
Urothelial carcinoma, pT2-4 G30.30.30.3
Mucoepidermoid carcinoma of the salivary gland0.30.30.0
Papillary renal cell carcinoma0.30.00.0
Adenocarcinoma of the colon0.10.00.0
Clear cell renal cell carcinoma0.10.00.0