Clinical Significance of TUBGCP4 Expression in Hepatocellular Carcinoma

Table 1

Association between the expression of TUBGCP4 and clinicopathological features of HCC patients.

Variables	Total	TUBGCP4 staining
		Positive	Negative
Gender
Male	75	47	28	0.014	0.905
Female	5	3	2
Age (year)
<50	48	28	20	0.889	0.346
≥50	32	22	10
Recurrence
No	27	18	9	0.302	0.583
Yes	53	32	21
Vascular tumor thrombus
No	21	14	7	0.211	0.646
Yes	59	36	23
HBV infection
No	13	8	5	0.002	0.968
Yes	66	41	25
Tumor number
<2	75	47	28	0.014	0.905
≥2	5	3	2
Portal vein tumor thrombus
Yes	79	49	30	0.608	0.436
No	1	1	0
Liver cirrhosis
No	42	28	14	0.655	0.418
Yes	38	22	16
Tumor capsule
No	30	19	11	0.014	0.905
Yes	50	31	19
Distant metastasis
No	76	48	28	0.281	0.596
Yes	4	2	2
Tumor grade
I + II	11	7	4	0.007	0.933
III + IV	69	43	26
TNM stage
T1 + T2	74	47	27	0.432	0.511
T3 + T4	6	3	3
CA-199 (U/mL)
≤37	62	35	27	4.301	0.038
>37	18	15	3
CEA (ng/mL)
≤5	74	46	28	0.048	0.826
>5	6	4	2
AFP (ng/mL)
<400	40	26	14	0.213	0.644
≥400	40	24	16

Notes: Bold values indicate significance.