Gallbladder Cancer Cell-Derived Exosome-Mediated Transfer of Leptin Promotes Cell Invasion and Migration by Modulating STAT3-Mediated M2 Macrophage Polarization

Figure 3

M2 macrophage induced by exosomal promotes invasion and migration of GBC-SD cells through leptin transfer. Transwell assay to detect invasion and migration of GBC-SD cell cocultured with macrophage treated with exosomes form si-control or si-leptin-transfected GBC-SD cell. Invasion and migration of GBC-SD cell were quantified. Data in (a) is representative of three independent experiments; the value was determined by Student’s test.

(a)

(b)