Impaired Deoxyribonuclease I Activity in Patients with Inflammatory Bowel Diseases

Table 1

Dynamics of DNase I activity and serum CRP concentration in IBD patients during the induction phase of biological treatment (n = 45).

	W0	W6	P-value*
DNase I activity (%)	67 (54,75)	68 (51,78 )	.724, NS
CRP (g/L)	31 (24, 39)	5 (1, 9)	<.001

Data are expressed as medians (interquartile range).
W0: week 0 of biological treatment; W6: week 6 of biological treatment; DNase I: deoxyribonuclease I; CRP: C-reactive protein; NS: nonsignificant
*Mann-Whitney U-test.