Lights and Shadows of Cyclophosphamide in the Treatment of Multiple Sclerosis

Table 3

Data obtained from 200 MS patients treated with cy in our centre over a ten-year period. *of the fertile women.

Side effects	%
Nausea and vomit	40
Amenorrhea	18*
Transitory amenorrhea	60*
Transitory azoospermia	60
Headache	15
Alopecia (reversible)	13
Fatigue	10
Diffuse pain	8
Cutaneous rash	6
Gastritis and diarrhoea	6
Bladder toxicity	6
Infection	3
Cancer risk	1
Arrhythmia	1
Dyspnoea	0.5