Autoimmune Diseases / 2012 / Article / Tab 2

Review Article

Evaluation of ENA-6 Profile by ELISA Immunoassay in Patients with Systemic Lupus Erythematodes

Table 2

Optimal cut-off, area under the curve with 95% confidence interval (AUC, 95% CI), sensitivity, specificity, positive and negative predictive value of ENA6, SM, and CIC in differencing between SLE patients and healthy control.

SLE patients versus healthy control
MarkerOptimal
cut-off
AUC (95% CI)Sensitivity (%)Specificity (%)Positive predictive value (%)Negative predictive value (%)

ENA6 Sm≥9,56 EU0,809 (0,690–0,928)70%100%100%76%
CIC≥54,24 EU0,931 (0,854–1,00)76%100%100%81%

SLE: systemic lupus erythematosus; AUC: area under the curve; CI: confidence interval; ENA6 Sm: extractable nuclear antigens 6 Sm; CIC: circulating immune complexes; EU: elisa units.

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