Improved Metabolic Control in Diabetes, HSP60, and Proinflammatory Mediators

Table 3

Summary of serum cytokine values reported from recent studies.

Reference	IL-1β pg/mL	IL-6 pg/mL	IL-8 pg/mL	IL-10 pg/mL	IL-12 pg/mL	TNFα pg/mL	Diabetes duration (Years)	Nationality
Mol et al. 1997 [24]	0.816					1.19	10 ± 7^*	Dutch
Adachi et al. 2004 [25]						2.4	Unknown	Japanese
Doganay et al. 2002 [26]	<0.05	<0.05	8.3			6.6	6.0±0.6	Turkish
Lee et al. 2008 [27]	0.94	1.47	5.11	0.77		3.95	9.0±5.4	Korean
Mishra et al. 2011^1 [28]		6.12			118	38.6	newly diagnosed	Indian
Mishra et al. 2011^2 [28]		9.55			147	50.8	newly diagnosed	Indian
McGee et al. 2011 [29]		7.03				16.9	1 yr. Minimum	British
Park et al. 2011 [30]		1.78					5.1	Korean
Hu et al. 2009^3 [31]		21.8				0.065	Unknown	Chinese
Hu et al. 2009^4 [31]		38.5				0.111	Unknown	Chinese
Ozturk et al. 2009 [32]		4.01	104.8	8.13			9.84±7.13	Turkish
Current Study	0	12.05	104.6	3.78	1.41	0.83	6.0±5.3	Italian

Values ± SEM except where indicated. Mishra et al. and Hu et al. both divided their diabetic populations into 2 groups: one by CRP and the other by presence or absence of evidence of atherosclerosis. Last row is baseline values for current study. ^*Standard deviation; ¹CRP< 3, ²CRP > 3; ³no evidence of atherosclerosis; ⁴evidence of atherosclerosis (increased carotid IMT).