Effect of Selenium on HLA-DR Expression of Thyrocytes

Table 1

Investigation of HLA-DR expression on thyrocytes induced by IFN-γ in the absence and presence of selenium. Figures in the table represent mean percentage DR positive human thyroid cells ±SD. All experiments were made in triplicate. ns. = not significant.

Culture of human thyrocytes	Expression of HLA-DR on thyrocytes (%)
Culture media (𝑛=4)	3.7±2.4	𝑃<0.001
IFN-γ (100 U/mL)	35.2±5.2		n.s	𝑃<0.05	𝑃<0.001
IFN-γ (100 U/mL) + sodium selenite (10 nM/mL) (𝑛=3)	33.2±14.7
IFN-γ (100 U/mL) + sodium selenite (50 nM/mL) (𝑛=3)	26.4±12.7
IFN-γ (100 U/mL) + sodium selenite (100 nM/mL) (𝑛=3)	11.5±5.2