Inflammatory Demyelinating Central Nervous System Diseases in Childhood: Clinical and Paraclinical Profiles in 133 Patients

Table 1

Clinical and demographic features of the 133 patients.

Topic
Female/male (𝑛)	84/49 (1.7 : 1)
The mean age at onset (y)	15.07 ± 2.72 (4–18)
The mean disease duration (y)	9.48±8.43 (1–44)
The mean EDSS score*	2.22±1.88 (0–9)
Age at onset (𝑛; f/m)
<12 years	15 (1.1 : 1)
≥12 years	118 (1.8 : 1)
<16 years	55 (1.3 : 1)
>16 years	78 (2.1 : 1)
Course of disease (𝑛; %)
RRMS	98 (73.7%)
SPMS	21 (15.8%)
CIS	8 (6%)
NMO	3 (2.3%)
Marburg	2 (1.5%)
RIS	1 (0.8%)

y: years; f/m: female/male; RRMS: relapsing remitting multiple sclerosis; SPMS: secondary progressive multiple sclerosis; CIS: clinically isolated syndrome; NMO: neuromyelitis optica; RIS: radiologically isolated syndrome.
*The EDSS scores were recorded during the last visit within 6 months before the study for 126 patients.