Clinical Study
The Role of Simvastatin in the Therapeutic Approach of Rheumatoid Arthritis
| Adverse event | Simvastatin group | Control group | |
| Elevated aspartate aminotransferase | 1 (2%) | 2 (4%) | 0.558 | Elevated alanine aminotransferase | 1 (2%) | 5 (10%) | 0.092 | Elevated creatine phosphokinase | 1 (2%) | 2 (4%) | 0.558 | Myalgia | 2 (4%) | 3 (6%) | 0.646 | Muscle weakness | 1 (2%) | 2 (4%) | 0.558 | Abdominal pain | 4 (8%) | 6 (12%) | 0.505 | Nausea | 6 (12%) | 4 (8%) | 0.505 | Constipation | 0 (0%) | 1 (2%) | 0.315 | Diarrhea | 0 (0%) | 1 (2%) | 0.315 | Flatulence | 1 (2%) | 2 (4%) | 0.558 | Asthenia | 2 (4%) | 4 (8%) | 0.400 | Dizziness | 1 (2%) | 3 (6%) | 0.307 | Headache | 2 (4%) | 4 (8%) | 0.400 | Allergy | 0 (0%) | 1 (2%) | 0.315 |
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