Susceptibility for Lupus Nephritis by Low Copy Number of the FCGR3B Gene Is Linked to Increased Levels of Pathogenic Autoantibodies

Table 1

Frequency of copy number (CN) variation in the FCGR3B gene in SLE patients and controls. Odds ratios with 95% confidence intervals (CI) for the association between FCGR3B gene copy number (CN) and SLE. Reference group is healthy controls (𝑛=162).

FCGR3B CN	SLE 𝑛=107	Controls 𝑛=162	OR	𝑃 value
<2	20%	6%	4.15 (CI: 1.82–29.46)	𝑃=0.0003
2	70%	86%	1
>2	9%	8%	1.03 (CI: 0.43–2.47)	𝑃=0.82

Global 𝜒² = 13.78, degrees of freedom = 2, and 𝑃=0.001.