Review Article

Neuroantibody Biomarkers: Links and Challenges in Environmental Neurodegeneration and Autoimmunity

Table 1

Serum/plasma half-life of some proteins proposed as biomarkers of neurodegeneration.

ProteinHalf-lifeReference

Neuron-specific enolase (NSE)48 hr[9]
S100β20–120 minutes[10, 11]
Glial fibrillary acidic protein (GFAP) 10–17 hr[12]
Myelin basic protein (MBP) 4 hr (plasma)
12 minutes (serum)
[13]