Understanding and Managing Pregnancy in Patients with Lupus

Table 3

Features differentiating preeclampsia and lupus nephritis.

Clinical and laboratory features	Preeclampsia	Lupus nephritis
Hypertension	After 20 weeks of gestation	Any time during pregnancy
Platelets	Low-normal	Low-normal
Complements	Normal-low	Rising titres
Anti-dsDNA	Absent or unchanged	Normal to raised
Creatinine	Normal to raised	Normal to raised
Serum uric acid	Elevated	Normal
24-hour urine calcium	<195 mg/dL	>195 mg/dL
Urinary sediment	Inactive	Active
Other organs involved	Occasionally CNS or HELLP	Evidence of active nonrenal SLE
Response to steroids	No	Yes