Urine Monocyte Chemoattractant Protein-1 and Lupus Nephritis Disease Activity: Preliminary Report of a Prospective Longitudinal Study

Figure 2

Receiver operating characteristic curve (ROC) of uMCP-1 compared with those of urinary parameters and SLEDAI-2K (renal) for the diagnosis of LN activity at 4 months. The black solid curve represents the uMCP-1; the area under the curve (AUC) was 0.87 (). The AUC for proteinuria was 0.89 () and those for haematuria and leukocyturia were 0.62 () and 0.62 (), respectively. The AUC for SLEDAI-2K was 0.85 (). Thus, uMCP-1 was better than haematuria and leukocyturia and essentially similar to proteinuria (uPCI) and SLEDAI-2K renal score for detection of LN activity at 4 months.