Research Article

Urine Monocyte Chemoattractant Protein-1 and Lupus Nephritis Disease Activity: Preliminary Report of a Prospective Longitudinal Study

Table 4

Association of uMCP-1 with parameters of LN activity on follow-up.

Spearman’s rho variable (active : inactive LN)Baseline (47 : 53)2 months (29 : 71)4 months (22 : 78)
value value value

Serum albumin−0.35 0.001−0.320.001−0.220.03
Serum creatinine0.090.380.14 0.150.240.01
eGFR−0.100.30−0.15 0.12−0.240.01
Anti-dsDNA Ab titers (IU)−0.040.64−0.19 0.060.010.89
C3 (mg/dL)−0.090.34−0.29 0.003−0.040.70
C4 (mg/dL)0.020.80−0.23 0.02−0.010.86
Proteinuria (uPCI)0.39 0.0010.48<0.0010.41<0.001
Leukocyturia0.26 0.0080.21 0.030.190.06
Haematuria0.130.180.09 0.380.110.24
SLEDAI-2K global score0.27 0.0060.42<0.0010.290.004
SLEDAI-2K renal score0.39 0.0010.43<0.0010.350.001
SLEDAI-2K-extrarenal score−0.080.42−0.180.74−0.11 0.27