Increased Circulating Th17 Cells, Serum IL-17A, and IL-23 in Takayasu Arteritis

Table 3

Comparison of Th17 expanders versus the rest.

Parameter	Patients with expansion of Th17 cells ()	Patients without expansion of Th17 cells ()	value
On immunosuppression	6/15	7/14	0.157
Active by Kerr’s criteria	7/15	6/14	0.157
ITAS2010	1 (0–8)	1 (0–10)	0.80
ITAS-A	3 (2–10)	3.5 (1.75–11.5)	0.73
Serum IL-17A	4.96 (4.72–8.39)	7.28 (4.29–8.78)	0.48
Serum IL-23	14.9 (14.9–26.38)	14.9 (14.9–19.37)	0.52

Values represented as median with interquartile range in brackets.
Th17 expanders were defined as those patients with TA having percentage of Th17 cells greater than 2 SD of the mean value of controls.
= ns for all comparisons between the two groups.