Clinical and Immunologic Profiles in Incomplete Lupus Erythematosus and Improvement with Hydroxychloroquine Treatment
Table 3
SLICC 2012 classification criteria in ILE and SLE patients.
Criterion
ILE ()
SLE ()
Clinical
Acute cutaneous
16 (22.5)
20 (64.5)
<0.0001
Chronic cutaneous
1 (1.4)
5 (16.1)
0.0095
NS
Oral ulcers
9 (12.7)
21 (67.7)
<0.0001
Alopecia
1 (1.4)
0 (0)
1.00
N/A
Synovitis
14 (19.7)
16 (51.6)
0.0019
Serositis
7 (9.9)
15 (48.4)
0.0001
Renal
0 (0)
4 (12.9)
0.0074
N/A
Neurologic
0 (0)
3 (9.7)
0.0262
N/A
Hemolytic
1 (1.4)
2 (6.5)
0.2185
NS
Leukopenia
4 (5.6)
11 (35.5)
0.0003
Thrombocytopenia
2 (2.8)
3 (9.7)
0.1630
NS
Immunologic
ANA
70 (98.6)
31 (100)
1.0
N/A
dsDNA
3 (4.2)
13 (41.9)
<0.0001
Sm
1 (1.4)
7 (22.6)
0.0009
APL
4 (5.6)
5 (16.1)
0.1261
NS
Complement
6 (8.5)
10 (32.3)
0.0057
NS
Coombs
0 (0)
0 (0)
N/A
N/A
See Table 2 footnotes. corr significance level after Bonferroni correction for multiple (13) comparisons: value less than 0.0038; value less than 0.00077.
