Research Article
Interference of Antinuclear Antibody (ANA) in Indirect Immunofluorescence Assay (IIFA)-Based Perinuclear Antineutrophil Cytoplasmic Antibody (pANCA) Interpretation
Table 1
ANA blot (ENA) results (with grading) versus pANCA positivity.
| S. No | ANA-blot (ENA blot) result grade | No of cases | pANCA positive (%) | Cohen's kappa | -Value (at significant level <0.05) |
| 01 | ++++ | 3 | 1 (33.3) | | 0.4224 | 02 | +++ | 23 | 5 (21.7) | | 0.4566 | 03 | ++ | 59 | 15 (25.4) | | 0.0248 | 04 | + | 34 | 8 (23.5) | | 0.2135 | 05 | (+)/- | 37 | 1 (2.7) | | 0.0131 | | Positives (overall) | 156 | 30 (19.2) | 0.822 | 0.0405 | | ANA-blot negative | 46 | 3 (6.5) | | |
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