Autoimmune Diseases

Multiple Sclerosis


Publishing date
01 Mar 2011
Status
Published
Submission deadline
01 Sep 2010

1Department of Clinical Neurology, University of Oxford, Oxford, UK

2Department of Medical Genetics, University of Calgary, Calgary, AB, Canada

3Department of Neuroimmunology, Blizard Institute of Cell and Molecular Science, Barts and the London School of Medicine and Dentistry, London, UK

4Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan


Multiple Sclerosis

Description

Multiple sclerosis (MS) is the commonest disease of the central nervous system (CNS) to cause permanent disability in young adults. Based on strong circumstantial evidence, MS is considered to be an organ-specific autoimmune disorder, but the exact cause is as yet unknown. It appears that the disease develops in a genetically susceptible population as a result of environmental exposures.

The incidence of MS has been documented to be increasing across the globe. The focus of this issue therefore will be on studies with a goal of further understanding the aetiology of the disease. Genetic, immunological, and epidemiological investigations are welcomed to help to elucidate the processes underlying MS causation. We are particularly interested in studies investigating:

  • The genetics/epigenetics of MS
  • The immunology of MS
  • The role of Epstein-Barr virus in MS
  • Vitamin D and its relationship to MS
  • Smoking and its relationship to MS
  • The use of new technologies/methods to understand MS pathogenesis, for example, whole genome sequencing, proteomics, and so forth

This list is not exhaustive, and other submissions fitting in with our main theme are welcome. We are also interested in receiving reviews covering any of the topics listed above.

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/ad/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2011
  • - Article ID 248758
  • - Editorial

Multiple Sclerosis

Sreeram Ramagopalan | David Dyment | ... | Noriko Isobe
  • Special Issue
  • - Volume 2011
  • - Article ID 519450
  • - Research Article

What is Next for the Genetics of Multiple Sclerosis?

Sreeram V. Ramagopalan | David A. Dyment
  • Special Issue
  • - Volume 2011
  • - Article ID 262847
  • - Review Article

Mitochondria as Crucial Players in Demyelinated Axons: Lessons from Neuropathology and Experimental Demyelination

Graham R. Campbell | Don J. Mahad
  • Special Issue
  • - Volume 2011
  • - Article ID 132958
  • - Research Article

A Nonsecosteroidal Vitamin D Receptor Modulator Ameliorates Experimental Autoimmune Encephalomyelitis without Causing Hypercalcemia

Songqing Na | Yanfei Ma | ... | Sunil Nagpal
  • Special Issue
  • - Volume 2011
  • - Article ID 485752
  • - Research Article

Effects of IFN-B on TRAIL and Decoy Receptor Expression in Different Immune Cell Populations from MS Patients with Distinct Disease Subtypes

Andrea L. O. Hebb | Craig S. Moore | ... | George S. Robertson
  • Special Issue
  • - Volume 2011
  • - Article ID 708750
  • - Review Article

Multiple Sclerosis: Are Protective Immune Mechanisms Compromised by a Complex Infectious Background?

Bernd Krone | John M. Grange
  • Special Issue
  • - Volume 2011
  • - Article ID 164608
  • - Review Article

Mechanisms of Oxidative Damage in Multiple Sclerosis and a Cell Therapy Approach to Treatment

Jonathan Witherick | Alastair Wilkins | ... | Kevin Kemp
  • Special Issue
  • - Volume 2011
  • - Article ID 932351
  • - Review Article

Heterogeneity in Multiple Sclerosis: Scratching the Surface of a Complex Disease

Giulio Disanto | Antonio J. Berlanga | ... | Julia M. Morahan
  • Special Issue
  • - Volume 2011
  • - Article ID 807426
  • - Review Article

MicroRNAs and Multiple Sclerosis

Kemal Ugur Tufekci | Meryem Gulfem Oner | ... | Kursad Genc
  • Special Issue
  • - Volume 2011
  • - Article ID 484936
  • - Research Article

Inhibition of Experimental Autoimmune Encephalomyelitis in Human C-Reactive Protein Transgenic Mice Is Fc š›¾ RIIB Dependent

Xian-Zhen Hu | Tyler T. Wright | ... | Alexander J. Szalai
Autoimmune Diseases
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