Functional Characterization of the Canine Heme-Regulated eIF2 Kinase: Regulation of Protein Synthesis
Figure 6
Effect of HRI inhibition on protein synthesis by quercetin in canine blood cells. Total protein synthesis in canine blood was determined by [35S]-methionine incorporation into newly synthesized protein in the presence of 1 or 10 M quercetin. The amounts of [35S]-methionine incorporation were compared to a vehicle control of 1% DMSO and the fold increase with the mean ± SEM from replicates is shown.