Research Article

Screening for Residual Disease in Pediatric Burkitt Lymphoma Using Consensus Primer Pools

Figure 2

MRD sensitivity with patient primary tumor DNA. Primary diagnostic tumor DNA (100% infiltrated with malignant cells) was diluted with PBMC DNA to represent the equivalent of 1 malignant cell in 103, 105, 107, 108, and 109 PBMC. Each representative melt curve has a distinct peak corresponding to tumor DNA or PBMC DNA, which are designated by the respective arrows.
412163.fig.002