Screening for Residual Disease in Pediatric Burkitt Lymphoma Using Consensus Primer Pools
Figure 2
MRD sensitivity with
patient primary tumor DNA. Primary diagnostic tumor DNA (100% infiltrated with
malignant cells) was diluted with PBMC DNA to represent the equivalent of 1
malignant cell in 103, 105, 107, 108,
and 109 PBMC. Each representative melt curve has a distinct peak
corresponding to tumor DNA or PBMC DNA, which are designated by the respective
arrows.