Research Article

An NMR Study of the Bortezomib Degradation under Clinical Use Conditions

Figure 3

Two possible degradation processes of BTZ in its pharmaceutical solution form (a) degradation pathway of boronic amino acids in presence of water or other nucleophilic agents; (b) oxidative degradation pathway of boronic acids.
704928.fig.003a
(a)
704928.fig.003b
(b)