ETV6-RUNX1 Rearrangement in Tunisian Pediatric B-Lineage Acute Lymphoblastic Leukemia

Figure 1

(a) an interphase cell with no translocation, (b) An interphase cell with two ETV6-RUNX1 fusion signals (yellow), (c) a metaphase cell with an ETV6-RUNX1 fusion signal and deletion of the second ETV6 allele (missing a red signal from the cell), (d) an interphase cell with ETV6-RUNX1 fusion signal and an extra copy of the RUNX1 gene, (e) two interphase cells with extra copies of the RUNX1 gene and without ETV6-RUNX1 fusion, (f) t(3;12) with a marker chromosome that harbored an extra copy of the RUNX1 gene.

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