Review Article

Diamond Blackfan Anemia at the Crossroad between Ribosome Biogenesis and Heme Metabolism

Figure 1

(a) Multiple roles of heme during erythroid cell differentiation. (b) Role of FLVCR1 during erythroid differentiation. (c) A model to explain how both FLVCR1, and RPS19 deficiencies may result in the failure of erythroid differentiation.
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(a)
790632.fig.001b
(b)
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(c)