Table of Contents Author Guidelines Submit a Manuscript
Advances in Hematology
Volume 2011, Article ID 258797, 6 pages
http://dx.doi.org/10.1155/2011/258797
Review Article

Role of Radiotherapy in Modern Treatment of Hodgkin's Lymphoma

Department of Clinical Oncology, Guy's and St. Thomas' Hospital, London, UK

Received 21 July 2010; Accepted 16 September 2010

Academic Editor: Nelson J. Chao

Copyright © 2011 Kheng-Wei Yeoh and N. George Mikhaeel. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Hodgkin's Lymphoma was incurable until the advent of effective therapeutic radiation around the first half of the 20th century. As survival rates improved, the long-term toxicities from radiotherapy began to emerge. This together with the availability of effective chemotherapy has encouraged a combined modality approach for early-staged disease and the omission of radiotherapy in advanced-staged disease. The differing toxicities of radiotherapy and chemotherapy has promoted ongoing research to identify the utility of each of these modalities in the modern management of Hodgkin's Lymphoma. This article will provide a critical review of the developments and indications for modern radiotherapy, in context with advances in chemotherapy, for the treatment of Hodgkin's Lymphoma.