Human Immunodeficiency Virus Infection and Hodgkin's Lymphoma in South Africa: An Emerging Problem

Table 1

Characteristics of patients (𝑛=29) with HIV-associated Hodgkin’s lymphoma seen at the Chris Hani Baragwanath Hospital (July 2008 to June 2010).

Patient characteristics	Number	%
Median age (range)—38 years (21–64) mean age—37 years (21–64)
Gender
Male	15	52
Female	14	48
Male : female ratio 1.1 : 1
ECOG performance status
0–2	18	62
3-4	11	38
“B” symptoms	27	93
Bone marrow involvement
Yes	10 (26)	38
No	16 (26)	62
Unknown	3	11
Stage of lymphoma
I-II	5 (28)	18
III-IV	23 (28)	82
Unclear	1	4
Histology
Mixed cellularity	13 (24)	54
Nodular sclerosis	8 (24)	33
Lymphocyte depleted	2 (24)	8
Lymphocyte rich	1 (24)	4
Unclassifiable/unknown	5	17
CD4 count in μl (range in μl)—mean CD4=176 (10–407)
>200/μl	11 (28)	39
<200/μl	17 (28)	61
<100/μl	9	31
<50/μl	6	21
Unknown	1	3
Risk factor for hiv infection
Heterosexual relation	29	100
Other (intravenous drug use, homosexual relation)	0
Duration of hiv
>1 Year	11	38
<1 Year	18	62
Use of antiretroviral therapy at diagnosis
Yes	13	45
No	16	55
True extranodal involvement (excluding liver, spleen, and bone marrow)	5	17
Liver involvement	13	45
Splenic involvement	8	28
Tuberculosis	17	59
Active disease	11	38
Past infection	6	21
Outcome
Alive	15	52
Dead	11	38
Ltfu (lost to follow up)	3	10