Human Immunodeficiency Virus Infection and Hodgkin's Lymphoma in South Africa: An Emerging Problem

Table 2

Salient differences between HIV-HL in South Africa and other reported series.

	South Africa (Chris Hani Baragwanath Hospital—CHBH)	Other reported series
Gender	M : F ratio,1.1 : 1	Majority male (>80%)
Median CD4 count	176/μl	240–306/μl (In different series)
Risk factors	Heterosexual relationship	Intravenous drug use and homosexual relationship
Diagnosis and duration of HIV	New diagnosis of HIV, 41%	Majority-established or long-standing HIV
	Duration of HIV <1 Year, 62%
ARV’s at diagnosis	45% on ARV’S	71–80% on ARV’S
	55% ARV naive
Tuberculosis	38% Active disease, 21% past, documented disease	Unknown (low prevalence)
Prognosis and overall survival	Generally unfavourable	Less favourable than HIV negative HL. Improving with standard chemotherapy and concomitant HAART