Hodgkin's Lymphoma: A Review of Neurologic Complications

Algorithm 1

Neurological complications of Hodgkin’s lymphoma.

Direct (metastatic)

   Intraparenchymal

   Dural

   Leptomeningeal

   Epidural spinal cord

Indirect

   Paraneoplastic

     Cerebellar degeneration

     Limbic encephalitis

   CNS angiitis

   Treatment-related

     Radiotherapy

       Dropped head syndrome

       Premature carotid artery atherosclerosis with cardiovascular complications

       Brachial plexopathy

     Chemotherapy

       Cardiomyopathy with CNS emboli and cardiovascular complications

       Toxic peripheral neuropathy