Advances in Hematology / 2011 / Article / Tab 2

Review Article

Neutropenia and Neutropenic Complications in ABVD Chemotherapy for Hodgkin Lymphoma

Table 2

Retrospective studies showing poor correlation between neutropenia and neutropenic complications.

AuthorNumber of analyzed patients without G-CSFGrade 4 neutropenia (%) patients/treatments1% of febrile neutropenia2% of growth factor supported treatmentsDM3 due to grade 3 or 4 neutropenia

Chand et al.8143/71.06.515.5% of all treatments
Evens et al.5926/NA40.440None
Boleti and Mead2837/NA0.570None
Nangalia et al.24NA/180.760None

1. Treatments are half cycles, that is, two treatments per cycle.
2. Incidence of febrile neutropenia as percentage of overall treatments (half cycles).
3. DM: dose modification.
4. NA: not available.