Review Article

Pathobiology of Hodgkin Lymphoma

Figure 2

Histopathological features of lymphocyte predominant Hodgkin lymphoma (LP-HL). At morphology (GIEMSA staining), it is possible to appreciate the nodular morphology (GM-I) and the typical LP cells (GM-II, arrow). At immunophenotyping, it is typically CD15-, CD30-, EMA+, CD45+, CD20+, and possibly (10%–20% cases) IgD+ (Olympus BX41 microscope, Olympus CAMEDIA C-7070 camera, magnification ×400, colours balanced after acquisition with Adobe Photoshop).
920898.fig.002