Microenvironment-Centred Dynamics in Aggressive B-Cell Lymphomas

Figure 1

Immune system cells, both adaptive and innate, engender a fertile microenvironment through direct interaction and release of factors in the milieu. (M: monocyte/macrophage; MC: mast cell; DC: dendritic cell; IDC: immature dentritic cell; MDSC: myeloid derived suppressor cell; T reg: T regulatory lymphocyte. Black arrows indicate activation pathways. Red lines indicate inhibitory pathways).